The Effect of Microbiome Exposure at Birth on Pediatric Outcomes Using a Twin Cohort Discordant for Microbiome Exposure at Birth

Abstract

The microbiome refers to the normal bacteria that live on our skin and in our bodies. There has been much written about the effect of differing microbiome exposures at birth and outcomes later in childhood and adulthood. In this study, we examined twins with differing microbiome exposure and found no differences at ages 2-10 years old, suggesting the importance of this variable may be overstated.

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“The Microbiome” – with Dr. Shari Gelber

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Serial Cervical Length Evaluation in Low-Risk Women with Shortened Cervical Lengths in the Midtrimester: How Many Will Dilate Prior to 24 Weeks?

For women diagnosed with a short cervix, there is controversy regarding the proper management and follow-up. In this study, we demonstrate that a significant proportion of women with a short cervix in the second trimester will ultimately have a dilated cervix, which is a more concerning situation and often requires different management. These results indicate that one should continue surveillance after the diagnosis of a short cervix.

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Induction of Labor versus Cesarean Delivery in Twin Pregnancies

Abstract

For women with twin pregnancies, we have previously shown that outcomes are similar for attempted vaginal delivery as compared to cesarean delivery. In this study, we demonstrate that this remains true even for women with twin pregnancies who require induction of labor.

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“Delivery of Twins – Double the Fun!” – with Dr. Stephanie Melka

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Subchorionic Hematomas and Adverse Pregnancy Outcomes among Twin Pregnancies

Abstract

Subchorionic hematomas, or subchorionic hemorrhages, are common ultrasound findings in early pregnancy. However, their significance is uncertain. Some believe they increase the risk of many pregnancy complications, including pregnancy loss / miscarriage. In prior studies we demonstrated that subchorionic hematoma does not appear to increase the risk adverse outcomes in singleton pregnancies.

In this study, we present similar results regarding twin pregnancies – subchorionic hematoma does not appear to increase the risk of adverse outcomes in twin pregnancies.

Prior Studies

Association Between First-Trimester Subchorionic Hematomas and Adverse Pregnancy Outcomes After 20 Weeks of Gestation in Singleton Pregnancies

Association Between First-Trimester Subchorionic Hematomas and Pregnancy Loss in Singleton Pregnancies

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Association Between First-Trimester Subchorionic Hematomas and Adverse Pregnancy Outcomes After 20 Weeks of Gestation in Singleton Pregnancies

Subchorionic hematomas, or subchorionic hemorrhages, are common ultrasound findings in early pregnancy. However, their significance is uncertain. Some believe they increase the risk of many pregnancy complications, including pregnancy loss / miscarriage. In a prior study we demonstrated that subchorionic hematoma does not appear to increase the risk of miscarriage in singleton pregnancies.

In this study, we present similar results regarding other adverse pregnancy outcomes – subchorionic hematoma does not appear to increase the risk of adverse outcomes later in pregnancy.

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COVID-19 in Pregnant Women: Case Series from One Large New York City Obstetrical Practice

Abstract

COVID-19 changed the world in 2020. One of the questions we get a lot is how it affects pregnant women. However, most studies only include hospitalized patients, making it seem like outcomes are worse than they might be. In this study, we report our experience with 92 pregnant women (approximately 12% of our pregnant patients) who had known or suspected COVID-19 infection. Fortunately, outcomes were very reassuring.